S54T (p.Ser54Thr) variant of PIM1 (P11309)
S54T (p.Ser54Thr) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
S54T (p.Ser54Thr) variant details
- p.Ser54Thr
- ExAC rs781178342
- TOPMed rs781178342
- gnomAD rs781178342
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.16
- CADD 23.50
- PolyPhen-2 0.09
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available