S51L (p.Ser51Leu) variant of PIM1 (P11309)
S51L (p.Ser51Leu) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
S51L (p.Ser51Leu) variant details
- p.Ser51Leu
- 1000Genomes rs551680157
- ExAC rs551680157
- TOPMed rs551680157
- gnomAD rs551680157
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.19
- CADD 24.30
- PolyPhen-2 0.24
- SIFT 0.00
- Most common in the 1KG:GWD population (allele frequency 0.0043)
- Structural context available