S46R (p.Ser46Arg) variant of PIM1 (P11309)
S46R (p.Ser46Arg) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
S46R (p.Ser46Arg) variant details
- p.Ser46Arg
- gnomAD 6-37170828-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.28
- CADD 22.40
- PolyPhen-2 0.09
- SIFT 0.35
- Population evidence available
- Structural context available
- Literature evidence available