R57H (p.Arg57His) variant of PIM1 (P11309)
R57H (p.Arg57His) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R57H (p.Arg57His) variant details
- p.Arg57His
- TOPMed rs1323508876
- Missense
- Variant Prioritization Score for Impact Estimate 0.407
- REVEL 0.24
- CADD 32.00
- PolyPhen-2 0.57
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available