P42S (p.Pro42Ser) variant of PIM1 (P11309)
P42S (p.Pro42Ser) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
P42S (p.Pro42Ser) variant details
- p.Pro42Ser
- gnomAD 6-37170814-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.33
- REVEL 0.07
- CADD 19.30
- PolyPhen-2 0.01
- SIFT 0.78
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available