P33A (p.Pro33Ala) variant of PIM1 (P11309)
P33A (p.Pro33Ala) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
P33A (p.Pro33Ala) variant details
- p.Pro33Ala
- 1000Genomes rs775870535
- ExAC rs775870535
- TOPMed rs775870535
- gnomAD rs775870535
- Missense
- Variant Prioritization Score for Impact Estimate 0.365
- REVEL 0.12
- CADD 21.00
- PolyPhen-2 0.01
- SIFT 0.44
- Most common in the Ashkenazi Jewish population (allele frequency 0.00029)
- Structural context available