L25V (p.Leu25Val) variant of PIM1 (P11309)
L25V (p.Leu25Val) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
L25V (p.Leu25Val) variant details
- p.Leu25Val
- 1000Genomes rs774607869
- ExAC rs774607869
- TOPMed rs774607869
- gnomAD rs774607869
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.09
- CADD 20.30
- PolyPhen-2 0.00
- SIFT 0.45
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available