L25R (p.Leu25Arg) variant of PIM1 (P11309)
L25R (p.Leu25Arg) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
L25R (p.Leu25Arg) variant details
- p.Leu25Arg
- TOPMed rs1310183432
- gnomAD rs1310183432
- Missense
- Variant Prioritization Score for Impact Estimate 0.223
- REVEL 0.07
- CADD 22.20
- PolyPhen-2 0.10
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available