K5T (p.Lys5Thr) variant of PIM1 (P11309)
K5T (p.Lys5Thr) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
K5T (p.Lys5Thr) variant details
- p.Lys5Thr
- gnomAD 6-37170589-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.23
- CADD 24.50
- PolyPhen-2 0.14
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available