K24R (p.Lys24Arg) variant of PIM1 (P11309)
K24R (p.Lys24Arg) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
K24R (p.Lys24Arg) variant details
- p.Lys24Arg
- gnomAD 6-37170646-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.06
- CADD 20.90
- PolyPhen-2 0.10
- SIFT 0.53
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available
- Literature evidence available