K24N (p.Lys24Asn) variant of PIM1 (P11309)
K24N (p.Lys24Asn) in PIM1 (P11309) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
K24N (p.Lys24Asn) variant details
- p.Lys24Asn
- NCI-TCGA Cosmic COSV6516
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.02
- CADD 16.90
- PolyPhen-2 0.06
- SIFT 0.48
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available