K24E (p.Lys24Glu) variant of PIM1 (P11309)
K24E (p.Lys24Glu) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
K24E (p.Lys24Glu) variant details
- p.Lys24Glu
- gnomAD rs1209123331
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.13
- CADD 19.80
- PolyPhen-2 0.22
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available