H21Q (p.His21Gln) variant of PIM1 (P11309)
H21Q (p.His21Gln) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
H21Q (p.His21Gln) variant details
- p.His21Gln
- ExAC rs746875868
- TOPMed rs746875868
- gnomAD rs746875868
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.07
- CADD 20.30
- PolyPhen-2 0.41
- SIFT 0.58
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available