H11R (p.His11Arg) variant of PIM1 (P11309)
H11R (p.His11Arg) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
H11R (p.His11Arg) variant details
- p.His11Arg
- gnomAD rs1263817223
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.07
- CADD 23.10
- PolyPhen-2 0.02
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available