G28V (p.Gly28Val) variant of PIM1 (P11309)
G28V (p.Gly28Val) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
G28V (p.Gly28Val) variant details
- p.Gly28Val
- gnomAD 6-37170773-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.351
- REVEL 0.08
- CADD 24.60
- PolyPhen-2 0.03
- SIFT 0.37
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available