F49L (p.Phe49Leu) variant of PIM1 (P11309)
F49L (p.Phe49Leu) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
F49L (p.Phe49Leu) variant details
- p.Phe49Leu
- gnomAD 6-37170835-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.444
- REVEL 0.37
- CADD 29.30
- PolyPhen-2 0.46
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available