E32D (p.Glu32Asp) variant of PIM1 (P11309)
E32D (p.Glu32Asp) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
E32D (p.Glu32Asp) variant details
- p.Glu32Asp
- gnomAD 6-37170786-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.192
- REVEL 0.12
- CADD 22.90
- PolyPhen-2 0.23
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available