C17Y (p.Cys17Tyr) variant of PIM1 (P11309)
C17Y (p.Cys17Tyr) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
C17Y (p.Cys17Tyr) variant details
- p.Cys17Tyr
- gnomAD 6-37170625-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.09
- CADD 21.10
- PolyPhen-2 0.01
- SIFT 0.44
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available