C17R (p.Cys17Arg) variant of PIM1 (P11309)
C17R (p.Cys17Arg) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
C17R (p.Cys17Arg) variant details
- p.Cys17Arg
- ExAC rs747616420
- Missense
- Variant Prioritization Score for Impact Estimate 0.282
- REVEL 0.14
- CADD 21.00
- PolyPhen-2 0.01
- SIFT 0.64
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available