A22T (p.Ala22Thr) variant of PIM1 (P11309)
A22T (p.Ala22Thr) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
A22T (p.Ala22Thr) variant details
- p.Ala22Thr
- ExAC rs776506228
- TOPMed rs776506228
- gnomAD rs776506228
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.07
- CADD 18.20
- PolyPhen-2 0.02
- SIFT 0.48
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available