A22S (p.Ala22Ser) variant of PIM1 (P11309)
A22S (p.Ala22Ser) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A22S (p.Ala22Ser) variant details
- p.Ala22Ser
- ExAC rs776506228
- TOPMed rs776506228
- gnomAD rs776506228
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.03
- CADD 15.40
- PolyPhen-2 0.04
- SIFT 0.83
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available