A10T (p.Ala10Thr) variant of PIM1 (P11309)
A10T (p.Ala10Thr) in PIM1 (P11309) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
A10T (p.Ala10Thr) variant details
- p.Ala10Thr
- gnomAD 6-37170603-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.389
- REVEL 0.12
- CADD 26.90
- PolyPhen-2 0.49
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- Literature evidence available