R16S (p.Arg16Ser) variant of PIK3R2 (O00459)
R16S (p.Arg16Ser) in PIK3R2 (O00459) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
R16S (p.Arg16Ser) variant details
- p.Arg16Ser
- 1000Genomes rs80233027
- ExAC rs80233027
- TOPMed rs80233027
- gnomAD rs80233027
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.03
- CADD 23.00
- PolyPhen-2 0.03
- SIFT 0.03
- EBI: Benign
- UniProt: Benign
- Population evidence available
- Structural context available