P14L (p.Pro14Leu) variant of PIK3R2 (O00459)
P14L (p.Pro14Leu) in PIK3R2 (O00459) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
P14L (p.Pro14Leu) variant details
- p.Pro14Leu
- cosmic curated COSV53224
- ExAC rs756943808
- TOPMed rs756943808
- gnomAD rs756943808
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.12
- CADD 19.70
- PolyPhen-2 0.01
- SIFT 0.09
- Population evidence available
- Structural context available