L25M (p.Leu25Met) variant of PIK3R2 (O00459)
L25M (p.Leu25Met) in PIK3R2 (O00459) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
L25M (p.Leu25Met) variant details
- p.Leu25Met
- gnomAD rs1369620029
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.26
- CADD 26.70
- PolyPhen-2 1.00
- SIFT 0.03
- Population evidence available
- Structural context available