L23M (p.Leu23Met) variant of PIK3R2 (O00459)
L23M (p.Leu23Met) in PIK3R2 (O00459) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L23M (p.Leu23Met) variant details
- p.Leu23Met
- cosmic curated COSV53224
- Ensembl rs2147944730
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.14
- CADD 25.10
- PolyPhen-2 0.62
- SIFT 0.01
- Population evidence available
- Structural context available