Y59F (p.Tyr59Phe) variant of PIK3R1 (P27986)
Y59F (p.Tyr59Phe) in PIK3R1 (P27986) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
Y59F (p.Tyr59Phe) variant details
- p.Tyr59Phe
- gnomAD 5-68226851-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.14
- CADD 15.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available