T63S (p.Thr63Ser) variant of PIK3R1 (P27986)
T63S (p.Thr63Ser) in PIK3R1 (P27986) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
T63S (p.Thr63Ser) variant details
- p.Thr63Ser
- gnomAD rs1444581630
- Missense
- Variant Prioritization Score for Impact Estimate 0.482
- REVEL 0.37
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available