T63P (p.Thr63Pro) variant of PIK3R1 (P27986)
T63P (p.Thr63Pro) in PIK3R1 (P27986) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
T63P (p.Thr63Pro) variant details
- p.Thr63Pro
- gnomAD rs1444581630
- Missense
- Variant Prioritization Score for Impact Estimate 0.526
- REVEL 0.43
- CADD 27.10
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available