R66T (p.Arg66Thr) variant of PIK3R1 (P27986)
R66T (p.Arg66Thr) in PIK3R1 (P27986) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
R66T (p.Arg66Thr) variant details
- p.Arg66Thr
- gnomAD 5-68226872-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.18
- CADD 25.30
- PolyPhen-2 0.90
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available