K15E (p.Lys15Glu) variant of PIK3R1 (P27986)
K15E (p.Lys15Glu) in PIK3R1 (P27986) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
K15E (p.Lys15Glu) variant details
- p.Lys15Glu
- gnomAD 5-68226718-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.24
- CADD 23.60
- PolyPhen-2 0.54
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available