G27S (p.Gly27Ser) variant of PIK3R1 (P27986)
G27S (p.Gly27Ser) in PIK3R1 (P27986) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
G27S (p.Gly27Ser) variant details
- p.Gly27Ser
- Ensembl rs2111963939
- Missense
- Variant Prioritization Score for Impact Estimate 0.599
- REVEL 0.53
- CADD 28.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available