R21W (p.Arg21Trp) variant of PIK3CG (P48736)
R21W (p.Arg21Trp) in PIK3CG (P48736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
R21W (p.Arg21Trp) variant details
- p.Arg21Trp
- cosmic curated COSV63248
- ExAC rs771734598
- TOPMed rs771734598
- gnomAD rs771734598
- Missense
- Variant Prioritization Score for Impact Estimate 0.385
- REVEL 0.35
- MetaLR 0.36
- MetaSVM -0.41
- CADD 25.60
- PolyPhen-2 0.80
- SIFT 0.00
- Population evidence available
- Structural context available