R21Q (p.Arg21Gln) variant of PIK3CG (P48736)
R21Q (p.Arg21Gln) in PIK3CG (P48736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
R21Q (p.Arg21Gln) variant details
- p.Arg21Gln
- ExAC rs755613711
- TOPMed rs755613711
- gnomAD rs755613711
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.22
- MetaLR 0.29
- MetaSVM -0.48
- CADD 23.20
- PolyPhen-2 0.27
- SIFT 0.07
- Population evidence available
- Structural context available