R21G (p.Arg21Gly) variant of PIK3CG (P48736)
R21G (p.Arg21Gly) in PIK3CG (P48736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
R21G (p.Arg21Gly) variant details
- p.Arg21Gly
- cosmic curated COSV10745
- ExAC rs771734598
- TOPMed rs771734598
- gnomAD rs771734598
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.16
- MetaLR 0.25
- MetaSVM -0.71
- CADD 22.90
- PolyPhen-2 0.01
- SIFT 0.10
- Population evidence available
- Structural context available