R18P (p.Arg18Pro) variant of PIK3CG (P48736)
R18P (p.Arg18Pro) in PIK3CG (P48736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R18P (p.Arg18Pro) variant details
- p.Arg18Pro
- 1000Genomes rs142380460
- ExAC rs142380460
- TOPMed rs142380460
- gnomAD rs142380460
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- REVEL 0.28
- MetaLR 0.34
- MetaSVM -0.56
- CADD 23.10
- PolyPhen-2 0.23
- SIFT 0.01
- Population evidence available
- Structural context available