R18L (p.Arg18Leu) variant of PIK3CG (P48736)
R18L (p.Arg18Leu) in PIK3CG (P48736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
R18L (p.Arg18Leu) variant details
- p.Arg18Leu
- 1000Genomes rs142380460
- ExAC rs142380460
- TOPMed rs142380460
- gnomAD rs142380460
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.18
- MetaLR 0.32
- MetaSVM -0.68
- CADD 20.70
- PolyPhen-2 0.03
- SIFT 0.00
- Population evidence available
- Structural context available