D15Y (p.Asp15Tyr) variant of PIK3CG (P48736)
D15Y (p.Asp15Tyr) in PIK3CG (P48736) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
D15Y (p.Asp15Tyr) variant details
- p.Asp15Tyr
- cosmic curated COSV63253
- ExAC rs761955149
- TOPMed rs761955149
- gnomAD rs761955149
- Missense
- Variant Prioritization Score for Impact Estimate 0.457
- REVEL 0.27
- MetaLR 0.36
- MetaSVM -0.32
- CADD 26.40
- PolyPhen-2 0.62
- SIFT 0.00
- Population evidence available
- Structural context available