G106D (p.Gly106Asp) variant of PIK3CD (O00329)
G106D (p.Gly106Asp) in PIK3CD (O00329) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
G106D (p.Gly106Asp) variant details
- p.Gly106Asp
- gnomAD rs1225852287
- Missense
- Variant Prioritization Score for Impact Estimate 0.518
- REVEL 0.34
- CADD 25.00
- PolyPhen-2 0.99
- SIFT 0.28
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available