V32L (p.Val32Leu) variant of PIK3CB (P42338)
V32L (p.Val32Leu) in PIK3CB (P42338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
V32L (p.Val32Leu) variant details
- p.Val32Leu
- ExAC rs775392228
- gnomAD rs775392228
- Missense
- Variant Prioritization Score for Impact Estimate 0.604
- CADD 19.60
- PolyPhen-2 0.03
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available