L36F (p.Leu36Phe) variant of PIK3CB (P42338)
L36F (p.Leu36Phe) in PIK3CB (P42338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
L36F (p.Leu36Phe) variant details
- p.Leu36Phe
- cosmic curated COSV10000
- gnomAD rs1295285143
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- CADD 23.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available