L35P (p.Leu35Pro) variant of PIK3CB (P42338)
L35P (p.Leu35Pro) in PIK3CB (P42338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L35P (p.Leu35Pro) variant details
- p.Leu35Pro
- Ensembl rs2108733950
- Missense
- Variant Prioritization Score for Impact Estimate 0.654
- CADD 27.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available