I75T (p.Ile75Thr) variant of PIK3CB (P42338)
I75T (p.Ile75Thr) in PIK3CB (P42338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data.
I75T (p.Ile75Thr) variant details
- p.Ile75Thr
- TOPMed rs1187901141
- Missense
- Variant Prioritization Score for Impact Estimate 0.506
- CADD 22.50
- PolyPhen-2 0.19
- SIFT 0.38
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)