G133S (p.Gly133Ser) variant of PIK3CB (P42338)
G133S (p.Gly133Ser) in PIK3CB (P42338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.83 / 1. The record also includes population frequency data and structural context.
G133S (p.Gly133Ser) variant details
- p.Gly133Ser
- gnomAD rs1323215077
- Missense
- Variant Prioritization Score for Impact Estimate 0.835
- CADD 35.00
- PolyPhen-2 0.47
- SIFT 0.04
- Most common in the Ashkenazi Jewish population (allele frequency 4.1e-05)
- Structural context available