F69Y (p.Phe69Tyr) variant of PIK3CB (P42338)
F69Y (p.Phe69Tyr) in PIK3CB (P42338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data.
F69Y (p.Phe69Tyr) variant details
- p.Phe69Tyr
- ExAC rs758784705
- gnomAD rs758784705
- Missense
- Variant Prioritization Score for Impact Estimate 0.498
- CADD 22.30
- PolyPhen-2 0.12
- SIFT 0.38
- Most common in the African/African-American population (allele frequency 3e-05)