D21Y (p.Asp21Tyr) variant of PIK3CB (P42338)
D21Y (p.Asp21Tyr) in PIK3CB (P42338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.73 / 1. The record also includes population frequency data.
D21Y (p.Asp21Tyr) variant details
- p.Asp21Tyr
- TOPMed rs576986268
- Missense
- Variant Prioritization Score for Impact Estimate 0.732
- CADD 23.50
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 5.4e-06)