A25S (p.Ala25Ser) variant of PIK3CB (P42338)
A25S (p.Ala25Ser) in PIK3CB (P42338) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data.
A25S (p.Ala25Ser) variant details
- p.Ala25Ser
- ESP rs374448453
- ExAC rs374448453
- TOPMed rs374448453
- gnomAD rs374448453
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- CADD 14.80
- PolyPhen-2 0.03
- SIFT 0.75
- Most common in the Non-Finnish European population (allele frequency 9e-07)