R4G (p.Arg4Gly) variant of PIK3CA (P42336)
R4G (p.Arg4Gly) in PIK3CA (P42336) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R4G (p.Arg4Gly) variant details
- p.Arg4Gly
- TOPMed rs1051397
- gnomAD rs1051397
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.40
- MetaLR 0.24
- MetaSVM -0.77
- CADD 23.20
- PolyPhen-2 0.69
- SIFT 0.20
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available