P5Q (p.Pro5Gln) variant of PIK3CA (P42336)
P5Q (p.Pro5Gln) in PIK3CA (P42336) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
P5Q (p.Pro5Gln) variant details
- p.Pro5Gln
- gnomAD 3-179198839-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.567
- REVEL 0.48
- MetaLR 0.40
- MetaSVM -0.30
- CADD 25.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available