P2T (p.Pro2Thr) variant of PIK3CA (P42336)
P2T (p.Pro2Thr) in PIK3CA (P42336) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
P2T (p.Pro2Thr) variant details
- p.Pro2Thr
- gnomAD 3-179198829-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- REVEL 0.42
- MetaLR 0.28
- MetaSVM -0.63
- CADD 22.60
- PolyPhen-2 0.04
- SIFT 0.12
- Population evidence available
- Structural context available
- Literature evidence available